Cart
sales@molnova.com
Homo-PROTAC cereblon degrader 1
CAS No. 2244520-98-5
Homo-PROTAC cereblon degrader 1 ( —— )
Catalog No. M21750 CAS No. 2244520-98-5
Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 516 | Get Quote |
|
| 10MG | 740 | Get Quote |
|
| 25MG | 1125 | Get Quote |
|
| 50MG | 1521 | Get Quote |
|
| 100MG | 2052 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameHomo-PROTAC cereblon degrader 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionHomo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
-
DescriptionHomo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2244520-98-5
-
Formula Weight660.63
-
Molecular FormulaC32H32N6O10
-
Purity>98% (HPLC)
-
SolubilityDMSO : 200 mg/mL (302.74 mM; Need ultrasonic)
-
SMILESO=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCOCCOCCNC4=C5C(C(N(C6CCC(NC6=O)=O)C5=O)=O)=CC=C4)=C3C1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.
molnova catalog
related products
-
ZXH-3-26
ZXH-3-26 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), shows activity exclusively on the BRD4 BD1 (DC50/5h=5 nM) and spares degradation of BRD2 or BRD3 in cellular degradation assays.
-
SNIPER(ABL)-062
SNIPER(ABL)-062 is a novel, potent SNIPER molecule that tethers BCR-ABL inhibitor to a ligand of IAP, causes potent BCR-ABL degradation.
-
A1874
A1874 is a nutlin-based and BRD4-degrading PROTAC with a DC50 of 32 nM (induce BRD4 degradation in cells). Effective in inhibiting many cancer cell lines proliferation.
