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Homo-PROTAC cereblon degrader 1
CAS No. 2244520-98-5
Homo-PROTAC cereblon degrader 1( —— )
Catalog No. M21750 CAS No. 2244520-98-5
Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 516 | Get Quote |
|
| 10MG | 740 | Get Quote |
|
| 25MG | 1125 | Get Quote |
|
| 50MG | 1521 | Get Quote |
|
| 100MG | 2052 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHomo-PROTAC cereblon degrader 1
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NoteResearch use only, not for human use.
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Brief DescriptionHomo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
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DescriptionHomo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2244520-98-5
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Formula Weight660.63
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Molecular FormulaC??H??N?O??
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Purity>98% (HPLC)
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SolubilityDMSO : 200 mg/mL (302.74 mM; Need ultrasonic)
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SMILESO=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCOCCOCCNC4=C5C(C(N(C6CCC(NC6=O)=O)C5=O)=O)=CC=C4)=C3C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.
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